Sugar Causes Gout Since diabetes is caused by weight
Sugar Causes Gout Since diabetes is caused by weight, it also can lead to gout development. Sugar causes gout because fructose is metabolized differently than glucose (Arthritis Foundation, 2017). When fructose is digested, it releases chemicals called purines, and creates uric acid (Arthritis Foundation, 2017). Then, uric acid develops painful crystals (they are made of sodium urate although they are referred to as uric acid crystals) in the joints and eventually causes gout (Arthritis Foundation, 2017).
In addition, myassignmenthelp reviews showed people who drank two or more sugary drinks a day had an 85 percent increased risk for developing gout rather than people who had less than a soda a month (Arthritis Foundation, 2017). Furthermore, being overweight due to high sugary foods and drinks can lead to a greater risk of developing gout since your weight affects the kidneys’ ability to remove uric acid (Arthritis Foundation, 2017). Also, people who have gout can become more likely to develop diabetes due to the fructose in the body converting to uric acid (Arthritis Foundation, 2017). In addition, sometimes, a persons’ kidneys do not function properly and cannot excrete enough uric acid, eventually causing gout (Arthritis Foundation, 2017). In addition, you can also develop a disease called hyperuricemia which is an excess of uric acid in the bloodstream, caused by eating too many foods high in fructose (Arthritis Foundation, 2017). Because fructose goes to the liver, fructose then becomes fructose-1-phosphate, causing a reduction in ATP levels (Thomas, 2019). Then, when there becomes an increase in AMP (Adenosine monophosphate), the AMP will be converted to IMP (Integral membrane protein) instead (Thomas, 2019).
When increasing fructose intake and lowering ATP levels, it leads to an increase in purine production with uric acid becoming a side effect (Thomas, 2019). Symptoms of having gout include intense joint pain (usually happens in the big toe but can happen in any joint (Mayo Clinic Staff, 2019). Joints can also include elbows, wrists, and fingers (Mayo Clinic Staff, 2019). Pain becomes more severe in the first twelve hours), lingering discomfort (happens from a few days to a few weeks), inflammation (joint becomes swollen, warm, and red), and decreased range of motion (as gout becomes more severe, you may have limited movement in your joints) (Mayo Clinic Staff, 2019). Foods which develop gout include foods with high purine content like seafood and liver (Warren, 2019). Then, you will get hyperuricemia which leads to gout (Warren, 2019).
Foods to help prevent gout include low purine foods like vegetables and plant-based proteins since they help lower purine intake and decrease uric acid levels (Anbari, 2019). In addition, gout can progress to arthritis if it is untreated. While sugar can cause gout, it also increases joint pain (arthritis and inflammation). Foods with excessive amounts of sugar increase CRP (C-reactive proteins) levels (Brandy, 2015). This is because sugary foods cause insulin spikes, result in many biochemical reactions, and cause inflammation (Brandy, 2015). Also, visceral fat leaks out inflammatory proteins and causes chronic inflammation (Brandy, 2015). In addition, more studies have shown a buildup of AGEs in joint tissues cause changes in the articular cartilage and the cartilage becomes more vulnerable to damage (Brandy, 2015). To continue, when you eat simple sugars, your body will begin to flood with stress hormones and insulin (Organic Excellence, 2013).
These chemicals go into the blood, trigger the inflammation process, and then create stress and pain on the joints (Organic Excellence, 2013). Furthermore, another study showed drinking a can of soda which has 40 grams of sugar daily increased the risk of inflammatory markers and LDL cholesterol (Brown, 2017). Also, another myassignmenthelp review showed when obese people had one can of soda a day for six months had increased uric acid levels which increased their chances of developing inflammation and insulin resistance (Brown, 2017).
To add on, another study showed eating 50 grams of refined carbohydrates resulted in higher blood sugar levels and an increased amount of an inflammatory marker called Nf-kB (Brown, 2017). In addition, bacteria and undigested food particles become easier to move out of the gut and into the bloodstream, causing inflammation (Brown, 2017). In addition, there are three reasons why we may get inflammation; gut microbial imbalance (comes from low fiber and high sugar diets), intestinal permeability (happens with processed foods), and gluten consumption (caused by the release of a protein called zonulin which helps keep the permeability between cells) (King-Nosser, 2015).